A small town in Oregon is home to the greatest scientific minds on the planet. Hilarity prevails.
Literally anything can happen, whether it makes scientific sense or not. Thankfully most problems (the town becoming animated, drone robots with bad personalities, a swimming pool that simultaneously combusts and haphazard time travel for example) are usually solvable with some bravado from the friendly sheriff (who has an average IQ – Chortle) and a particle / photon / protein accelerator / magnet / fluid.
My favourite is when they just decide to skip to an alternate reality and basically start the whole series from scratch with zero explanation. Audacious!
Seriously stupid. Really addictive.